Scientific Programme

Thursday 19 June, 2008

8:00-10:00

(1) EADO SESSION
Question about prevention and early detection of melanoma

Chairs: Ketty Peris (Italy),Antonio Ribas (USA), Marie-Aleth Richard (France)

8:00

Prevention

  • What is the real role of ultraviolet radiation in the different types of melanoma?
    Martin Weinstock (USA)

8:20

  • Do epidemiological trends of melanoma suggest an efficacy of sun prevention?
    Luigi Naldi (Italy)

8:40

Early detection and surveillance of nevi

  • Is education to the community cost effective for early detection of melanoma?
    Alex Stratigos (Greece)

9:00
  • Monitoring techniques (mole mapping, computerized dermoscopy …):
    cost-effective or time consuming?
    Michael Binder (Austria)

9:20
  • Dysplastic nevi in 2008
    Josep Malvehy (Spain)

9:40
  • Kinetics of melanoma growth: an impact on early detection?
    Jean-Jacques Grob (France)

10:30-12:30

(2) ICATMM SESSION
Adjuvant therapy: what have we learnt?

Sponsored by an educational grant from GlaxoSmithKline

Chairs: Brigitte Dreno (France), John M. Kirkwood (USA), Spyros Retsas (United Kingdom)

10:30

How can we select subgroups for adjuvant therapy?

  • High troughput expression studies in primary culaneous melanoma
    Alain Spatz (France)

10:50
  • Risk markers: surgical staging
    Vernon Sondak (USA)

11:10
  • Risk markers: disease staging: present and future
    Jeffrey Gerschenwald (USA)

11:30
  • Response predictors: auto-immunity
    Helen Gogas (Greece)

11:50
  • Response predictors: tumor markers and markers of residual disease
    Selma Ugurel (Germany)

12:10
  • Detection of residual disease during surveillance: imaging and ultrasound
    Philippe Saiag (France)

14:30-15:50

(2)ICATMM SESSION
Adjuvant therapy: what have we learnt?
Sponsored by an educational grant from GlaxoSmithKline

Chairs: Sanjiv S.Agarwala (USA), Hubert Pehamberger (Austria), Philippe Saiag (France)

14:30

Current status of the adjuvant therapy

  • Surgical adjuvant therapy: elective node dissection according to sentinel node status: Pro
    Merrick Ross (USA)

14:50
  • Sentinel lymph node biopsy in melanoma is not the Holy Grail
    Joseph Meirion Thomas (United Kingdom)

15:10
  • Twenty years of adjuvant therapy studies with Interferon alpha, who benefits?
    Alexander Eggermont (The Netherlands)
15:30
  • Adjuvant therapy with Interferons: pegylated interferons
    Claus Garbe (Germany)

16:30-18:15

FREE ORAL COMMUNICATIONS 1
Chairs: Michael Binder (Austria), Jeffrey E. Gershenwald (USA), Peter Hersey (Australia)

18:30-19:30

SATELLITE SYMPOSIUM jointly sponsored by the American Academy of CME and
North American Medical Education
Immunotherapy For Advanced Melanoma
Redefining Treatment Expectations

Chair: John Kirkwood (USA)
Speakers: Alexander Eggermont (The Netherlands), Patrick Hwu (USA), Caroline Robert (France), Dirk Schadendorf (Germany)

  • Recent clinical trial evidence regarding immunotherapies including anti-CTLA-4 inhibitors
  • Kinetics of anti-CTLA-4 inhibitors and relevance to treatment decision-making and monitoring of response
  • Detection and management of immunotherapy-related adverse events
  • Optimizing treatment for individual patients

Educational grants provided by Bristol-Myers Squibb and Pfizer

 

Friday 20 June, 2008

8:00-10:00

(3) EADO & ICATMM SESSION
New strategies: from first results in metastatic melanoma to the application in the adjuvant therapy
Chairs: Sergio Chimenti (Italy),Alexander Eggermont (The Netherlands), Daniel Olive (France),Vernon Sondak (USA)

8:00

Targeted therapies and combinations

  • Targeting kinase and signalling pathways
    Paul Nathan (United Kingdom)

8:20
  • Targeting mTOR
    Friedegund Meier (Germany)
8:40
  • Targeting resistance to apoptosis
    Hubert Pehamberger (Austria)

9:00
  • Targeting histone deacetylase and DNA hypermethylation
    Peter Hersey (Australia)

9:20
  • Targeting heat shock proteins, chaperones and proteasomes
    Keith Flaherty (USA)

9:40
  • Synthesis:What potential place in the palliative and adjuvant strategy?
    (results of clinical trials)
    Axel Hauschild (Germany)

10:30-11:10

(3) EADO & ICATMM SESSION
New strategies: from first results in metastatic melanoma to the application in the adjuvant therapy

Chairs: Caroline Robert (France), Martin A.Weinstock (USA)

10:30

New development in chemotherapy and combinations

  • Recent advances in chemotherapy and chemo-immunotherapy of melanoma
    Sanjiv S.Agarwala (USA
10:50
  • Combining chemotherapy and targeted therapy
    Alessandro Testori (Italy)

11:10-12:30

FREE ORAL COMMUNICATIONS 2
Chairs: Helen Gogas (Greece), Roland Kaufmann (Germany), Paul Nathan (United Kingdom), Alessandro Testori (Italy)

14:30-16:30

(3) EADO & ICATMM SESSION:
New strategies: from first results in metastatic melanoma to the application in the adjuvant therapy
Chairs: Charles Balch (USA), Claus Garbe (Germany), Jean-Jacques Grob (France)

14:30

New development in immunotherapy and potential application in adjuvant setting

  • Immune responses and melanoma
    Daniel Olive (France)
14:50
  • New approaches using cytokines
    John M. Kirkwood (USA)
15:10
  • Vaccination dendritic cells approach
    Dirk Schadendorf (Germany)
15:30
  • What’s new in adoptive immunotherapy
    Brigitte Dreno (France)
15:50
  • Anti CTLA4 and combination
    Antoni Ribas (USA)
16:10
  • Place of natural immunity modulation
    Reinhard Dummer (Switzerland)

17:00-18:00

(3) EADO & ICATMM SESSION:
New strategies: from first results in metastatic melanoma to the application in the adjuvant therapy
Chairs: Keith Flaherty (USA),Axel Hauschild (Germany)

17:00

New development in immunotherapy and potential application in adjuvant setting

  • Using the sentinel lymph node as a target for adjuvant therapy
    Tanja D. de Gruijl (The Netherlands)
17:20
  • Synthesis:What potential place in the palliative and adjuvant strategy?
    Caroline Robert (France)
17:40
  • Systemic treatment of metastatic melanoma. Quo vadis oncologist?
    Spyros Retsas (United Kingdom)

18:30-19:30

SATELLITE SYMPOSIUM sponsored by SCHERING-PLOUGH
Melanoma Care: From Retrospective to Perspective

Chair: Jean-Jacques Grob (France)

18:30
  • Opening Remarks
    Jean-Jacques Grob (France)
18:35
  • Succinct survey of new criteria for predicting risk in melanoma surgical patients: Update on AJCC staging
    Charles Balch (USA)
18:45
  • Adjuvant Interferon alpha for melanoma: Summary review of randomized trials
    Axel Hauschild (Germany)
18:55
  • EORTC 18991: Pegylated IFN vs observation in stage III melanoma: Overview of the role of tumor load and ulceration of primary melanoma
    Alexander Eggermont (The Netherlands)
19:15
  • Adjuvant therapy for melanoma:What are we waiting for?
    Vernon Sondak (USA)
19:25
  • Questions & Answers

 

Saturday 21 June, 2008

8:00-9:30
(4) EADO SESSSION
Chairs: Merrick Ross (USA), Dirk Schadendorf (Germany), Selma Ugurel (Germany)

8:00

Non surgical treatments of non melanoma skin cancers (actinic keratoses, invasive squamous cell carcinoma and basal cell carcinoma)

  • Is field cancerization more than a concept?
    Eggert Stockfleth (Germany)
8:15
  • Do we need to treat all actinic keratoses?
    Martin A.Weinstock (USA
8:30
  • Best indications of Solaraze
    Hubert Pehamberger (Austria)
8:45
  • Best indications of 5 FU
    Eggert Stockfleth (Germany)
9:00
  • Best indications of Imiquimod
    Sergio Chimenti (Italy)
9:15
  • What place for cryotherapy, PTD and laser in the treatment of actinic keratosis?
    Marie-Aleth Richard (France)

9:30-10:00

FREE ORAL COMMUNICATIONS 3
Chairs: Merrick Ross (USA), Dirk Schadendorf (Germany), Selma Ugurel (Germany)

10:30-11:00

(4) EADO SESSION
Chair: Susana Puig (Spain)

10:30

Genetic counselling in melanoma

  • The genetics of melanoma
    Julia A. Newton-Bishop (United Kingdom)
10:45
  • What practical impact of genetic counselling?
    Ketty Peris (Italy)

11:00-12:30

(4) EADO SESSION
Chair: Julia A. Newton-Bishop (United Kingdom), Eggert Stockfleth (Germany)

11:00

Managing cutaneous lymphoma

  • Better understanding how to classify common and rare forms of skin lymphoma
    Marie Beylot-Barry (France)
11:15
  • Physiopathology of mycosis fungoides
    Martine Bagot (France)

11:30

  • Recent results in the treatment of mycosis fungoides
    Reinhard Dummer (Switzerland)
11:45
  • Refractory T cell skin lymphoma
    Roland Kaufmann (Germany)
12:00
  • Managing pseudo-lymphomas and low grades lymphomas
    Hervé Bachelez (France)
12:15
  • Managing Cutaneous Lymphoma
    Réda Bouabdallah (France)

 

Open investigator meetings

Friday, June 20th, 2008

13:00
14:00
  • OPEN INVESTIGATOR MEETING
    organised by GENTA: Genasense® (oblimersen sodium)
    Auditorium

17:30
19:00

  • OPEN INVESTIGATOR MEETING
    organised by BIRKEN GmbH: Oleogel-S-10 (betulinic acid) in patients with actinic keratoses
    Room Phar’Club (level 1, main building of the Palais du Pharo)